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has served as the definitive bridge between basic science and clinical medicine for over seven decades. The 31st edition continues this legacy, moving beyond a simple catalog of chemical reactions to provide a map of human life at the atomic level. 1. The Integration of Form and Function The core philosophy of Harper’s is that pathology is the language of broken biochemistry

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Edisi ke-31 dari Biokimia Harper merupakan update terbaru yang menyajikan konsep-konsep terkini dalam biokimia. Edisi ini tidak hanya membahas dasar-dasar biokimia seperti struktur dan fungsi biomolekul, metabolisme, dan genetika molekuler, tetapi juga mendiskusikan bagaimana biokimia terkait dengan kondisi kesehatan dan penyakit.

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| | Chapters Covered | | :--- | :--- | | Structures & Functions of Proteins & Enzymes | 1. Biochemistry & Medicine 2. Water & pH 3. Amino Acids & Peptides 4. Proteins: Determination of Primary Structure 5. Proteins: Higher Orders of Structure 6. Proteins: Myoglobin & Hemoglobin | | Enzymes: Kinetics, Mechanism, Regulation, & Role of Transition Metals | 7. Enzymes: Mechanism of Action 8. Enzymes: Kinetics 9. Enzymes: Regulation of Activities 10. The Biochemical Roles of Transition Metals | | Bioenergetics | 11. Bioenergetics: The Role of ATP 12. Biologic Oxidation 13. The Respiratory Chain & Oxidative Phosphorylation | | Metabolism of Carbohydrates | 14. Overview of Metabolism & the Provision of Metabolic Fuels 15. Carbohydrates of Physiological Significance 16. The Citric Acid Cycle: The Central Pathway of Carbohydrate, Lipid, & Amino Acid Metabolism 17. Glycolysis & the Oxidation of Pyruvate 18. Metabolism of Glycogen 19. Gluconeogenesis & the Control of Blood Glucose 20. The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism | | Metabolism of Lipids | 21. Lipids of Physiologic Significance 22. Oxidation of Fatty Acids: Ketogenesis 23. Biosynthesis of Fatty Acids & Eicosanoids 24. Metabolism of Acylglycerols & Sphingolipids 25. Lipid Transport & Storage 26. Cholesterol Synthesis, Transport, & Excretion | | Metabolism of Proteins & Amino Acids | 27. Biosynthesis of the Nutritionally Nonessential Amino Acids 28. Catabolism of Proteins & of Amino Acid Nitrogen 29. Catabolism of the Carbon Skeletons of Amino Acids 30. Conversion of Amino Acids to Specialized Products 31. Porphyrins & Bile Pigments | | Structure, Function, & Replication of Informational Macromolecules | 32. Nucleotides 33. Metabolism of Purine & Pyrimidine Nucleotides 34. Nucleic Acid Structure & Function 35. DNA Organization, Replication, & Repair 36. RNA Synthesis, Processing, & Modifications 37. Protein Synthesis & the Genetic Code 38. Regulation of Gene Expression 39. Molecular Genetics, Recombinant DNA, & Genomic Technology | | Biochemistry of Extracellular & Intracellular Communication | 40. Membranes: Structure & Function 41. The Diversity of the Endocrine System 42. Hormone Action & Signal Transduction | | Special Topics | 43. Nutrition, Digestion, & Absorption 44. Vitamins & Minerals 45. Intracellular Traffic & Sorting of Proteins 46. Glycoproteins 47. The Extracellular Matrix 48. Muscle & the Cytoskeleton 49. Plasma Proteins & Immunoglobulins 50. Hemostasis & Thrombosis 51. Red & White Blood Cells 52. Metabolism of Xenobiotics 53. The Human Genome Project |

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